Identification of Protective Pneumococcal T(H)17 Antigens from the Soluble Fraction of a Killed Whole Cell Vaccine

Mucosal or parenteral immunization with a killed unencapsulated pneumococcal whole cell antigen (WCA) with an adjuvant protects mice from colonization by a T(H)17 CD4+ cell-mediated mechanism. Using preparative SDS gels, we separated the soluble proteins that compose the WCA in order to identify fra...

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Detalles Bibliográficos
Autores principales: Moffitt, Kristin L., Malley, Richard, Lu, Ying-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419164/
https://www.ncbi.nlm.nih.gov/pubmed/22905267
http://dx.doi.org/10.1371/journal.pone.0043445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419164/
https://www.ncbi.nlm.nih.gov/pubmed/22905267
http://dx.doi.org/10.1371/journal.pone.0043445

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