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Identifying the Genetic Variation of Gene Expression Using Gene Sets: Application of Novel Gene Set eQTL Approach to PharmGKB and KEGG

Genetic variation underlying the regulation of mRNA gene expression in humans may provide key insights into the molecular mechanisms of human traits and complex diseases. Current statistical methods to map genetic variation associated with mRNA gene expression have typically applied standard linkage...

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Detalles Bibliográficos
Autores principales: Abo, Ryan, Jenkins, Gregory D., Wang, Liewei, Fridley, Brooke L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419168/
https://www.ncbi.nlm.nih.gov/pubmed/22905253
http://dx.doi.org/10.1371/journal.pone.0043301