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Identifying the Genetic Variation of Gene Expression Using Gene Sets: Application of Novel Gene Set eQTL Approach to PharmGKB and KEGG
Genetic variation underlying the regulation of mRNA gene expression in humans may provide key insights into the molecular mechanisms of human traits and complex diseases. Current statistical methods to map genetic variation associated with mRNA gene expression have typically applied standard linkage...
Autores principales: | Abo, Ryan, Jenkins, Gregory D., Wang, Liewei, Fridley, Brooke L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419168/ https://www.ncbi.nlm.nih.gov/pubmed/22905253 http://dx.doi.org/10.1371/journal.pone.0043301 |
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