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The Germinal Center Kinase TNIK Is Required for Canonical NF-κB and JNK Signaling in B-Cells by the EBV Oncoprotein LMP1 and the CD40 Receptor

The tumor necrosis factor-receptor-associated factor 2 (TRAF2)- and Nck-interacting kinase (TNIK) is a ubiquitously expressed member of the germinal center kinase family. The TNIK functions in hematopoietic cells and the role of TNIK-TRAF interaction remain largely unknown. By functional proteomics...

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Detalles Bibliográficos
Autores principales: Shkoda, Anna, Town, Jennifer A., Griese, Janine, Romio, Michael, Sarioglu, Hakan, Knöfel, Thomas, Giehler, Fabian, Kieser, Arnd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419181/
https://www.ncbi.nlm.nih.gov/pubmed/22904686
http://dx.doi.org/10.1371/journal.pbio.1001376