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Acute Peripheral but Not Central Administration of Olanzapine Induces Hyperglycemia Associated with Hepatic and Extra-Hepatic Insulin Resistance

Atypical antipsychotic drugs such as Olanzapine induce weight gain and metabolic changes associated with the development of type 2 diabetes. The mechanisms underlying the metabolic side-effects of these centrally acting drugs are still unknown to a large extent. We compared the effects of peripheral...

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Detalles Bibliográficos
Autores principales: Girault, Elodie M., Alkemade, Anneke, Foppen, Ewout, Ackermans, Mariëtte T., Fliers, Eric, Kalsbeek, Andries
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419184/
https://www.ncbi.nlm.nih.gov/pubmed/22905238
http://dx.doi.org/10.1371/journal.pone.0043244