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Virotherapy Using Myxoma Virus Prevents Lethal Graft-versus-Host Disease following Xeno-Transplantation with Primary Human Hematopoietic Stem Cells

Graft-versus-host disease (GVHD) is a potentially lethal clinical complication arising from the transfer of alloreactive T lymphocytes into immunocompromised recipients. Despite conventional methods of T cell depletion, GVHD remains a major challenge in allogeneic hematopoietic cell transplant. Here...

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Detalles Bibliográficos
Autores principales: Bartee, Eric, Meacham, Amy, Wise, Elizabeth, Cogle, Christopher R., McFadden, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419197/
https://www.ncbi.nlm.nih.gov/pubmed/22905251
http://dx.doi.org/10.1371/journal.pone.0043298