Positive Selection on the Osteoarthritis-Risk and Decreased-Height Associated Variants at the GDF5 Gene in East Asians

GDF5 is a member of the bone morphogenetic protein (BMP) gene family, and plays an important role in the development of the skeletal system. Variants of the gene are associated with osteoarthritis and height in some human populations. Here, we resequenced the gene in individuals from four geographic...

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Detalles Bibliográficos
Autores principales: Wu, Dong-Dong, Li, Gui-Mei, Jin, Wei, Li, Yan, Zhang, Ya-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419199/
https://www.ncbi.nlm.nih.gov/pubmed/22905146
http://dx.doi.org/10.1371/journal.pone.0042553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419199/
https://www.ncbi.nlm.nih.gov/pubmed/22905146
http://dx.doi.org/10.1371/journal.pone.0042553

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