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Synthetic Virus-Like Particles Target Dendritic Cell Lipid Rafts for Rapid Endocytosis Primarily but Not Exclusively by Macropinocytosis

DC employ several endocytic routes for processing antigens, driving forward adaptive immunity. Recent advances in synthetic biology have created small (20–30 nm) virus-like particles based on lipopeptides containing a virus-derived coiled coil sequence coupled to synthetic B- and T-cell epitope mime...

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Detalles Bibliográficos
Autores principales: Sharma, Rajni, Ghasparian, Arin, Robinson, John A., McCullough, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419204/
https://www.ncbi.nlm.nih.gov/pubmed/22905240
http://dx.doi.org/10.1371/journal.pone.0043248