Dietary Heme-Mediated PPARα Activation Does Not Affect the Heme-Induced Epithelial Hyperproliferation and Hyperplasia in Mouse Colon

Red meat consumption is associated with an increased colon cancer risk. Heme, present in red meat, injures the colon surface epithelium by luminal cytotoxicity and reactive oxygen species. This surface injury is overcompensated by hyperproliferation and hyperplasia of crypt cells. Transcriptome anal...

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Detalles Bibliográficos
Autores principales: IJssennagger, Noortje, de Wit, Nicole, Müller, Michael, van der Meer, Roelof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419209/
https://www.ncbi.nlm.nih.gov/pubmed/22905243
http://dx.doi.org/10.1371/journal.pone.0043260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419209/
https://www.ncbi.nlm.nih.gov/pubmed/22905243
http://dx.doi.org/10.1371/journal.pone.0043260

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