In Vitro Silencing of Brugia malayi Trehalose-6-Phosphate Phosphatase Impairs Embryogenesis and In Vivo Development of Infective Larvae in Jirds

BACKGROUND: The trehalose metabolic enzymes have been considered as potential targets for drug or vaccine in several organisms such as Mycobacterium, plant nematodes, insects and fungi due to crucial role of sugar trehalose in embryogenesis, glucose uptake and protection from stress. Trehalose-6-pho...

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Detalles Bibliográficos
Autores principales: Kushwaha, Susheela, Singh, Prashant Kumar, Shahab, Mohd., Pathak, Manisha, Bhattacharya, Shailja Misra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419221/
https://www.ncbi.nlm.nih.gov/pubmed/22905273
http://dx.doi.org/10.1371/journal.pntd.0001770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419221/
https://www.ncbi.nlm.nih.gov/pubmed/22905273
http://dx.doi.org/10.1371/journal.pntd.0001770

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