The Acute Phase Reactant Orosomucoid-1 Is a Bimodal Regulator of Angiogenesis with Time- and Context-Dependent Inhibitory and Stimulatory Properties

BACKGROUND: Tissues respond to injury by releasing acute phase reaction (APR) proteins which regulate inflammation and angiogenesis. Among the genes upregulated in wounded tissues are tumor necrosis factor-alpha (TNFα) and the acute phase reactant orosomucoid-1 (ORM1). ORM1 has been shown to modulat...

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Detalles Bibliográficos
Autores principales: Ligresti, Giovanni, Aplin, Alfred C., Dunn, Bruce E., Morishita, Ann, Nicosia, Roberto F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419235/
https://www.ncbi.nlm.nih.gov/pubmed/22916107
http://dx.doi.org/10.1371/journal.pone.0041387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419235/
https://www.ncbi.nlm.nih.gov/pubmed/22916107
http://dx.doi.org/10.1371/journal.pone.0041387

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