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Associations between Purine Metabolites and Clinical Symptoms in Schizophrenia

BACKGROUND: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology of schizophrenia. METHODOLOGY/PRINCIPAL FINDI...

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Detalles Bibliográficos
Autores principales: Yao, Jeffrey K., Condray, Ruth, Dougherty, George G., Keshavan, Matcheri S., Montrose, Debra M., Matson, Wayne R., McEvoy, Joseph, Kaddurah-Daouk, Rima, Reddy, Ravinder D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419238/
https://www.ncbi.nlm.nih.gov/pubmed/22916123
http://dx.doi.org/10.1371/journal.pone.0042165