Cargando…

FTY720 Protects Cardiac Microvessels of Diabetes: A Critical Role of S1P1/3 in Diabetic Heart Disease

Background: Diabetes is associated with an increased risk of cardiac microvascular disease. The mechanisms by which this damage occurs are unknown. However, research suggests that signaling through the sphingosine-1-phosphates receptor 1 and 3 (S1P1/3) by FTY720, a sphiongolipid drug that is structu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Zhiyong, Fan, Linni, Wei, Liping, Gao, Haokao, Zhang, Rongqing, Tao, Ling, Cao, Feng, Wang, Haichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419247/
https://www.ncbi.nlm.nih.gov/pubmed/22916176
http://dx.doi.org/10.1371/journal.pone.0042900