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Design Space Approach in Optimization of Fluid Bed Granulation and Tablets Compression Process

The aim of this study was to optimize fluid bed granulation and tablets compression processes using design space approach. Type of diluent, binder concentration, temperature during mixing, granulation and drying, spray rate, and atomization pressure were recognized as critical formulation and proces...

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Detalles Bibliográficos
Autores principales: Djuriš, Jelena, Medarević, Djordje, Krstić, Marko, Vasiljević, Ivana, Mašić, Ivana, Ibrić, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419407/
https://www.ncbi.nlm.nih.gov/pubmed/22919295
http://dx.doi.org/10.1100/2012/185085