Albumin induces upregulation of matrix metalloproteinase-9 in astrocytes via MAPK and reactive oxygen species-dependent pathways

BACKGROUND: Astrocytes are an integral component of the blood–brain barrier (BBB) which may be compromised by ischemic or traumatic brain injury. In response to trauma, astrocytes increase expression of the endopeptidase matrix metalloproteinase (MMP)-9. Compromise of the BBB leads to the infiltrati...

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Detalles Bibliográficos
Autores principales: Ranaivo, Hantamalala Ralay, Hodge, Jessica N, Choi, Nicole, Wainwright, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419618/
https://www.ncbi.nlm.nih.gov/pubmed/22507553
http://dx.doi.org/10.1186/1742-2094-9-68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419618/
https://www.ncbi.nlm.nih.gov/pubmed/22507553
http://dx.doi.org/10.1186/1742-2094-9-68

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