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Albumin induces upregulation of matrix metalloproteinase-9 in astrocytes via MAPK and reactive oxygen species-dependent pathways
BACKGROUND: Astrocytes are an integral component of the blood–brain barrier (BBB) which may be compromised by ischemic or traumatic brain injury. In response to trauma, astrocytes increase expression of the endopeptidase matrix metalloproteinase (MMP)-9. Compromise of the BBB leads to the infiltrati...
Autores principales: | Ranaivo, Hantamalala Ralay, Hodge, Jessica N, Choi, Nicole, Wainwright, Mark S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419618/ https://www.ncbi.nlm.nih.gov/pubmed/22507553 http://dx.doi.org/10.1186/1742-2094-9-68 |
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