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Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit
Aging and atherosclerosis are well-recognized risk factors for cardiac and neurovascular diseases. The Apolipoprotein E deficient (ApoE−/−) mouse on a high-fat diet is a classical model of atherosclerosis, characterized by the presence of atherosclerotic plaques in extracranial vessels but not in ce...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419627/ https://www.ncbi.nlm.nih.gov/pubmed/22709928 http://dx.doi.org/10.1186/1742-2094-9-132 |