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Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

Aging and atherosclerosis are well-recognized risk factors for cardiac and neurovascular diseases. The Apolipoprotein E deficient (ApoE−/−) mouse on a high-fat diet is a classical model of atherosclerosis, characterized by the presence of atherosclerotic plaques in extracranial vessels but not in ce...

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Detalles Bibliográficos
Autores principales: Badaut, Jérôme, Copin, Jean-Christophe, Fukuda, Andrew M, Gasche, Yvan, Schaller, Karl, da Silva, Rafaela F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419627/
https://www.ncbi.nlm.nih.gov/pubmed/22709928
http://dx.doi.org/10.1186/1742-2094-9-132