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Protease-Activated Receptor 2 Mediates Mucus Secretion in the Airway Submucosal Gland

Protease-activated receptor 2 (PAR2), a G protein-coupled receptor expressed in airway epithelia and smooth muscle, plays an important role in airway inflammation. In this study, we demonstrated that activation of PAR2 induces mucus secretion from the human airway gland and examined the underlying m...

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Detalles Bibliográficos
Autores principales: Lee, Hyun Jae, Yang, Yu-Mi, Kim, Kyubo, Shin, Dong Min, Yoon, Joo-Heon, Cho, Hyung-Ju, Choi, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419645/
https://www.ncbi.nlm.nih.gov/pubmed/22916223
http://dx.doi.org/10.1371/journal.pone.0043188