Single Nucleotide Polymorphism Array Lesions, TET2, DNMT3A, ASXL1 and CBL Mutations Are Present in Systemic Mastocytosis

We hypothesized that analysis of single nucleotide polymorphism arrays (SNP-A) and new molecular defects may provide new insight in the pathogenesis of systemic mastocytosis (SM). SNP-A karyotyping was applied to identify recurrent areas of loss of heterozygosity and bidirectional sequencing was per...

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Detalles Bibliográficos
Autores principales: Traina, Fabiola, Visconte, Valeria, Jankowska, Anna M., Makishima, Hideki, O’Keefe, Christine L., Elson, Paul, Han, Yingchun, Hsieh, Fred H., Sekeres, Mikkael A., Mali, Raghuveer Singh, Kalaycio, Matt, Lichtin, Alan E., Advani, Anjali S., Duong, Hien K., Copelan, Edward, Kapur, Reuben, Olalla Saad, Sara T., Maciejewski, Jaroslaw P., Tiu, Ramon V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419680/
https://www.ncbi.nlm.nih.gov/pubmed/22905207
http://dx.doi.org/10.1371/journal.pone.0043090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419680/
https://www.ncbi.nlm.nih.gov/pubmed/22905207
http://dx.doi.org/10.1371/journal.pone.0043090

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