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Drosophila EYA Regulates the Immune Response against DNA through an Evolutionarily Conserved Threonine Phosphatase Motif

Innate immune responses against DNA are essential to counter both pathogen infections and tissue damages. Mammalian EYAs were recently shown to play a role in regulating the innate immune responses against DNA. Here, we demonstrate that the unique Drosophila eya gene is also involved in the response...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Sano, Teruyuki, Guan, Yongsheng, Nagata, Shigekazu, Hoffmann, Jules A., Fukuyama, Hidehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419738/
https://www.ncbi.nlm.nih.gov/pubmed/22916150
http://dx.doi.org/10.1371/journal.pone.0042725