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Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies

BACKGROUND: Despite focused research in conventional therapies and considerable advances in the understanding of the molecular carcinogenesis of head and neck squamous cell carcinoma (HNSCC), the 5-year survival rate for patients with advanced disease remains ∼15–20%. The major causes of HNSCC-relat...

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Detalles Bibliográficos
Autores principales: St John, M A, Wang, G, Luo, J, Dohadwala, M, Hu, D, Lin, Y, Dennis, M, Lee, J M, Elashoff, D, Lawhon, T, Zaknoen, S L, Burrows, F J, Dubinett, S M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419945/
https://www.ncbi.nlm.nih.gov/pubmed/22828609
http://dx.doi.org/10.1038/bjc.2012.203