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A randomised study evaluating the use of pyridoxine to avoid capecitabine dose modifications

BACKGROUND: Pyridoxine is frequently used to treat capecitabine-induced hand–foot syndrome (HFS), although the evidence of benefit is lacking. We performed a randomised placebo-controlled trial to determine whether pyridoxine could avoid the need for capecitabine dose modifications and improve outco...

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Detalles Bibliográficos
Autores principales: Corrie, P G, Bulusu, R, Wilson, C B, Armstrong, G, Bond, S, Hardy, R, Lao-Sirieix, S, Parashar, D, Ahmad, A, Daniel, F, Hill, M, Wilson, G, Blesing, C, Moody, A M, McAdam, K, Osborne, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419962/
https://www.ncbi.nlm.nih.gov/pubmed/22814578
http://dx.doi.org/10.1038/bjc.2012.318