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Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer

BACKGROUND: MicroRNA (miRNA)-126 (miR-126) is an endothelial-specific miRNA located within intron 7 of epidermal growth factor-like domain 7 (EGFL7). However, the role of miR-126 in cancer is controversial. METHODS: We examined the function of miR-126 in oral squamous cell carcinoma (OSCC) cells. Fu...

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Detalles Bibliográficos
Autores principales: Sasahira, T, Kurihara, M, Bhawal, U K, Ueda, N, Shimomoto, T, Yamamoto, K, Kirita, T, Kuniyasu, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419968/
https://www.ncbi.nlm.nih.gov/pubmed/22836510
http://dx.doi.org/10.1038/bjc.2012.330