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BSA Nanoparticles for siRNA Delivery: Coating Effects on Nanoparticle Properties, Plasma Protein Adsorption, and In Vitro siRNA Delivery

Developing vehicles for the delivery of therapeutic molecules, like siRNA, is an area of active research. Nanoparticles composed of bovine serum albumin, stabilized via the adsorption of poly-L-lysine (PLL), have been shown to be potentially inert drug-delivery vehicles. With the primary goal of red...

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Detalles Bibliográficos
Autores principales: Yogasundaram, Haran, Bahniuk, Markian Stephan, Singh, Harsh-Deep, Aliabadi, Hamidreza Montezari, Uludağ, Hasan, Unsworth, Larry David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420107/
https://www.ncbi.nlm.nih.gov/pubmed/22919392
http://dx.doi.org/10.1155/2012/584060