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Cathepsin D Expression in Colorectal Cancer: From Proteomic Discovery through Validation Using Western Blotting, Immunohistochemistry, and Tissue Microarrays

Despite recent advances in surgical techniques and therapeutic treatments, survival from colorectal cancer (CRC) remains disappointing with some 40–50% of newly diagnosed patients ultimately dying of metastatic disease. Current staging by light microscopy alone is not sufficiently predictive of prog...

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Detalles Bibliográficos
Autores principales: Kirana, Chandra, Shi, Hongjun, Laing, Emma, Hood, Kylie, Miller, Rose, Bethwaite, Peter, Keating, John, Jordan, T. William, Hayes, Mark, Stubbs, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420108/
https://www.ncbi.nlm.nih.gov/pubmed/22919486
http://dx.doi.org/10.1155/2012/245819