Cargando…

The Transmembrane Domains of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Receptors 1 and 2 Co-Regulate Apoptotic Signaling Capacity

TNF-related apoptosis-inducing ligand (TRAIL) is a member of the tumor necrosis factor (TNF) ligand family that exerts its apoptotic activity in human cells by binding to two transmembrane receptors, TRAILR1 and TRAILR2. In cells co-expressing both receptors the particular contribution of either pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Neumann, Simon, Bidon, Tobias, Branschädel, Marcus, Krippner-Heidenreich, Anja, Scheurich, Peter, Doszczak, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420232/
https://www.ncbi.nlm.nih.gov/pubmed/22916132
http://dx.doi.org/10.1371/journal.pone.0042526