CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species

CD137 (4-1BB, TNFRSF9), a member of the tumor necrosis factor (TNF) receptor family, is a potent T cell co-stimulatory molecule. CD137 ligand (CD137L) is expressed by antigen presenting cells (APC) as a transmembrane protein and transmits activating signals into APC. In this study we investigated th...

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Detalles Bibliográficos
Autores principales: Yeo, Yee Andy, Martínez Gómez, Julia M, Croxford, J Ludovic, Gasser, Stephan, Ling, Eng-Ang, Schwarz, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420242/
https://www.ncbi.nlm.nih.gov/pubmed/22799524
http://dx.doi.org/10.1186/1742-2094-9-173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420242/
https://www.ncbi.nlm.nih.gov/pubmed/22799524
http://dx.doi.org/10.1186/1742-2094-9-173

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