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CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species

CD137 (4-1BB, TNFRSF9), a member of the tumor necrosis factor (TNF) receptor family, is a potent T cell co-stimulatory molecule. CD137 ligand (CD137L) is expressed by antigen presenting cells (APC) as a transmembrane protein and transmits activating signals into APC. In this study we investigated th...

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Detalles Bibliográficos
Autores principales:	Yeo, Yee Andy, Martínez Gómez, Julia M, Croxford, J Ludovic, Gasser, Stephan, Ling, Eng-Ang, Schwarz, Herbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420242/ https://www.ncbi.nlm.nih.gov/pubmed/22799524 http://dx.doi.org/10.1186/1742-2094-9-173

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