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Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury

BACKGROUND: Perinatal brain injury is complex and often associated with both inflammation and hypoxia-ischaemia (HI). In adult inflammatory brain injury models, therapies to increase acetylation are efficacious in reducing inflammation and cerebral injury. Our aim in the present study was to examine...

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Detalles Bibliográficos
Autores principales: Fleiss, Bobbi, Nilsson, Marie KL, Blomgren, Klas, Mallard, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420244/
https://www.ncbi.nlm.nih.gov/pubmed/22512781
http://dx.doi.org/10.1186/1742-2094-9-70