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P2X(7) signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand

BACKGROUND: The cerebral microvascular occlusion elicits microvascular injury which mimics the different degrees of stroke severity observed in patients, but the mechanisms underlying these embolic injuries are far from understood. The Fas ligand (FasL)-Fas system has been implicated in a number of...

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Detalles Bibliográficos
Autores principales: Lu, Ying-mei, Tao, Rong-rong, Huang, Ji-yun, Li, Li-tao, Liao, Mei-hua, Li, Xiao-ming, Fukunaga, Kohji, Hong, Ze-Hui, Han, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420259/
https://www.ncbi.nlm.nih.gov/pubmed/22789015
http://dx.doi.org/10.1186/1742-2094-9-172