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P2X(7) signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand
BACKGROUND: The cerebral microvascular occlusion elicits microvascular injury which mimics the different degrees of stroke severity observed in patients, but the mechanisms underlying these embolic injuries are far from understood. The Fas ligand (FasL)-Fas system has been implicated in a number of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420259/ https://www.ncbi.nlm.nih.gov/pubmed/22789015 http://dx.doi.org/10.1186/1742-2094-9-172 |