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Self-renewal of thymocytes in the absence of competitive precursor replenishment
Soon after transplantation of wild-type thymi into immunodeficient mice lacking functional T cell receptors, productive T cell development in the donor thymus ceases. This observation underlies one of the central dogmas of T cell biology: because thymocytes are seemingly short-lived, intrathymic T c...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420333/ https://www.ncbi.nlm.nih.gov/pubmed/22851642 http://dx.doi.org/10.1084/jem.20121412 |