Cell-Nonautonomous Signaling of FOXO/DAF-16 to the Stem Cells of Caenorhabditis elegans

In Caenorhabditis elegans (C. elegans), the promotion of longevity by the transcription factor DAF-16 requires reduced insulin/IGF receptor (IIR) signaling or the ablation of the germline, although the reason for the negative impact of germ cells is unknown. FOXO/DAF-16 activity inhibits germline pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Wenjing, Huang, Xu, Neumann-Haefelin, Elke, Schulze, Ekkehard, Baumeister, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420913/
https://www.ncbi.nlm.nih.gov/pubmed/22916022
http://dx.doi.org/10.1371/journal.pgen.1002836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420913/
https://www.ncbi.nlm.nih.gov/pubmed/22916022
http://dx.doi.org/10.1371/journal.pgen.1002836

Ejemplares similares