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Cell-Nonautonomous Signaling of FOXO/DAF-16 to the Stem Cells of Caenorhabditis elegans

In Caenorhabditis elegans (C. elegans), the promotion of longevity by the transcription factor DAF-16 requires reduced insulin/IGF receptor (IIR) signaling or the ablation of the germline, although the reason for the negative impact of germ cells is unknown. FOXO/DAF-16 activity inhibits germline pr...

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Detalles Bibliográficos
Autores principales:	Qi, Wenjing, Huang, Xu, Neumann-Haefelin, Elke, Schulze, Ekkehard, Baumeister, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420913/ https://www.ncbi.nlm.nih.gov/pubmed/22916022 http://dx.doi.org/10.1371/journal.pgen.1002836

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