Identification and Targeting of an Interaction between a Tyrosine Motif within Hepatitis C Virus Core Protein and AP2M1 Essential for Viral Assembly

Novel therapies are urgently needed against hepatitis C virus infection (HCV), a major global health problem. The current model of infectious virus production suggests that HCV virions are assembled on or near the surface of lipid droplets, acquire their envelope at the ER, and egress through the se...

Descripción completa

Detalles Bibliográficos
Autores principales: Neveu, Gregory, Barouch-Bentov, Rina, Ziv-Av, Amotz, Gerber, Doron, Jacob, Yves, Einav, Shirit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420927/
https://www.ncbi.nlm.nih.gov/pubmed/22916011
http://dx.doi.org/10.1371/journal.ppat.1002845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420927/
https://www.ncbi.nlm.nih.gov/pubmed/22916011
http://dx.doi.org/10.1371/journal.ppat.1002845

Ejemplares similares