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Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging

Prominent immune alterations associated with aging include the loss of naïve T-cell numbers, diversity and function. While genetic contributors and mechanistic details in the aging process have been addressed in multiple studies, the role of environmental agents in immune aging remains incompletely...

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Detalles Bibliográficos
Autores principales: Cicin-Sain, Luka, Brien, James D., Uhrlaub, Jennifer L., Drabig, Anja, Marandu, Thomas F., Nikolich-Zugich, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420928/
https://www.ncbi.nlm.nih.gov/pubmed/22916012
http://dx.doi.org/10.1371/journal.ppat.1002849