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Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with Aging
Prominent immune alterations associated with aging include the loss of naïve T-cell numbers, diversity and function. While genetic contributors and mechanistic details in the aging process have been addressed in multiple studies, the role of environmental agents in immune aging remains incompletely...
Autores principales: | Cicin-Sain, Luka, Brien, James D., Uhrlaub, Jennifer L., Drabig, Anja, Marandu, Thomas F., Nikolich-Zugich, Janko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420928/ https://www.ncbi.nlm.nih.gov/pubmed/22916012 http://dx.doi.org/10.1371/journal.ppat.1002849 |
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