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Experimental Relocation of the Mitochondrial ATP9 Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution

Only a few genes remain in the mitochondrial genome retained by every eukaryotic organism that carry out essential functions and are implicated in severe diseases. Experimentally relocating these few genes to the nucleus therefore has both therapeutic and evolutionary implications. Numerous unproduc...

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Detalles Bibliográficos
Autores principales: Bietenhader, Maïlis, Martos, Alexandre, Tetaud, Emmanuel, Aiyar, Raeka S., Sellem, Carole H., Kucharczyk, Roza, Clauder-Münster, Sandra, Giraud, Marie-France, Godard, François, Salin, Bénédicte, Sagot, Isabelle, Gagneur, Julien, Déquard-Chablat, Michelle, Contamine, Véronique, Denmat, Sylvie Hermann-Le, Sainsard-Chanet, Annie, Steinmetz, Lars M., di Rago, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420929/
https://www.ncbi.nlm.nih.gov/pubmed/22916027
http://dx.doi.org/10.1371/journal.pgen.1002876