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Experimental Relocation of the Mitochondrial ATP9 Gene to the Nucleus Reveals Forces Underlying Mitochondrial Genome Evolution
Only a few genes remain in the mitochondrial genome retained by every eukaryotic organism that carry out essential functions and are implicated in severe diseases. Experimentally relocating these few genes to the nucleus therefore has both therapeutic and evolutionary implications. Numerous unproduc...
Autores principales: | Bietenhader, Maïlis, Martos, Alexandre, Tetaud, Emmanuel, Aiyar, Raeka S., Sellem, Carole H., Kucharczyk, Roza, Clauder-Münster, Sandra, Giraud, Marie-France, Godard, François, Salin, Bénédicte, Sagot, Isabelle, Gagneur, Julien, Déquard-Chablat, Michelle, Contamine, Véronique, Denmat, Sylvie Hermann-Le, Sainsard-Chanet, Annie, Steinmetz, Lars M., di Rago, Jean-Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420929/ https://www.ncbi.nlm.nih.gov/pubmed/22916027 http://dx.doi.org/10.1371/journal.pgen.1002876 |
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