Rates of Gyrase Supercoiling and Transcription Elongation Control Supercoil Density in a Bacterial Chromosome

Gyrase catalyzes negative supercoiling of DNA in an ATP-dependent reaction that helps condense bacterial chromosomes into a compact interwound “nucleoid.” The supercoil density (σ) of prokaryotic DNA occurs in two forms. Diffusible supercoil density (σ(D)) moves freely around the chromosome in 10 kb...

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Detalles Bibliográficos
Autores principales: Rovinskiy, Nikolay, Agbleke, Andrews Akwasi, Chesnokova, Olga, Pang, Zhenhua, Higgins, N. Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420936/
https://www.ncbi.nlm.nih.gov/pubmed/22916023
http://dx.doi.org/10.1371/journal.pgen.1002845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420936/
https://www.ncbi.nlm.nih.gov/pubmed/22916023
http://dx.doi.org/10.1371/journal.pgen.1002845

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