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Genetics and Regulatory Impact of Alternative Polyadenylation in Human B-Lymphoblastoid Cells

Gene expression varies widely between individuals of a population, and regulatory change can underlie phenotypes of evolutionary and biomedical relevance. A key question in the field is how DNA sequence variants impact gene expression, with most mechanistic studies to date focused on the effects of...

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Detalles Bibliográficos
Autores principales: Yoon, Oh Kyu, Hsu, Tiffany Y., Im, Joo Hyun, Brem, Rachel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420953/
https://www.ncbi.nlm.nih.gov/pubmed/22916029
http://dx.doi.org/10.1371/journal.pgen.1002882