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Genetics and Regulatory Impact of Alternative Polyadenylation in Human B-Lymphoblastoid Cells
Gene expression varies widely between individuals of a population, and regulatory change can underlie phenotypes of evolutionary and biomedical relevance. A key question in the field is how DNA sequence variants impact gene expression, with most mechanistic studies to date focused on the effects of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420953/ https://www.ncbi.nlm.nih.gov/pubmed/22916029 http://dx.doi.org/10.1371/journal.pgen.1002882 |