Cargando…

Genetics and Regulatory Impact of Alternative Polyadenylation in Human B-Lymphoblastoid Cells

Gene expression varies widely between individuals of a population, and regulatory change can underlie phenotypes of evolutionary and biomedical relevance. A key question in the field is how DNA sequence variants impact gene expression, with most mechanistic studies to date focused on the effects of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Oh Kyu, Hsu, Tiffany Y., Im, Joo Hyun, Brem, Rachel B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420953/ https://www.ncbi.nlm.nih.gov/pubmed/22916029 http://dx.doi.org/10.1371/journal.pgen.1002882

Ejemplares similares

Alternative Polyadenylation: Methods, Findings, and Impacts
por: Chen, Wei, et al.
Publicado: (2017)

Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation
por: Xiao, Mei‐Sheng, et al.
Publicado: (2016)

Alternative polyadenylation mediates genetic regulation of gene expression
por: Mittleman, Briana E, et al.
Publicado: (2020)

Alternative polyadenylation of cyclooxygenase-2
por: Hall-Pogar, Tyra, et al.
Publicado: (2005)

Alternative Polyadenylation in Human Diseases
por: Chang, Jae-Woong, et al.
Publicado: (2017)

Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees
por: Mittleman, Briana E, et al.
Publicado: (2021)

Alternative polyadenylation-related genetic variants contribute to bladder cancer risk
por: Liu, Ting, et al.
Publicado: (2023)

Biased alternative polyadenylation in human tissues
por: Zhang, Haibo, et al.
Publicado: (2005)

Editorial: Alternative Polyadenylation in Development and Disease
por: Pai, Athma A., et al.
Publicado: (2022)

Regulation of alternative splicing and polyadenylation in neurons
por: Lee, Seungjae, et al.
Publicado: (2023)

RNA Regulatory Elements and Polyadenylation in Plants
por: Hunt, Arthur G.
Publicado: (2012)

Genome-wide mapping of polyadenylation sites in fission yeast reveals widespread alternative polyadenylation
por: Mata, Juan
Publicado: (2013)

Conservation of alternative polyadenylation patterns in mammalian genes
por: Ara, Takeshi, et al.
Publicado: (2006)

Transcriptional activity regulates alternative cleavage and polyadenylation
por: Ji, Zhe, et al.
Publicado: (2011)

Extensive alternative polyadenylation during zebrafish development
por: Ulitsky, Igor, et al.
Publicado: (2012)

Genome-wide dynamics of alternative polyadenylation in rice
por: Fu, Haihui, et al.
Publicado: (2016)

Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe
por: Liu, Xiaochuan, et al.
Publicado: (2017)

Dysfunctional transcripts are formed by alternative polyadenylation in OPMD
por: Raz, Vered, et al.
Publicado: (2017)

Template-switching artifacts resemble alternative polyadenylation
por: Balázs, Zsolt, et al.
Publicado: (2019)

Regulatory mechanisms for 3′-end alternative splicing and polyadenylation of the Glial Fibrillary Acidic Protein, GFAP, transcript
por: Blechingberg, Jenny, et al.
Publicado: (2007)

Alternative Polyadenylation Modification Patterns Reveal Essential Posttranscription Regulatory Mechanisms of Tumorigenesis in Multiple Tumor Types
por: Li, Min, et al.
Publicado: (2020)

UTR extension and alternate polyadenylation in neuroplasticity: an emerging paradigm?
por: Harrison, Benjamin J, et al.
Publicado: (2014)

Cell Cycle Regulation by Alternative Polyadenylation of CCND1
por: Wang, Qiong, et al.
Publicado: (2018)

Alternative polyadenylation factors link cell cycle to migration
por: Mitra, Mithun, et al.
Publicado: (2018)

The role of alternative polyadenylation in the antiviral innate immune response
por: Jia, Xin, et al.
Publicado: (2017)

The role of alternative Polyadenylation in regulation of rhythmic gene expression
por: Ptitsyna, Natalia, et al.
Publicado: (2017)

The transcriptional elongation rate regulates alternative polyadenylation in yeast
por: Geisberg, Joseph V, et al.
Publicado: (2020)

Extensive Involvement of Alternative Polyadenylation in Single-Nucleus Neurons
por: Wang, Ying, et al.
Publicado: (2020)

APAatlas: decoding alternative polyadenylation across human tissues
por: Hong, Wei, et al.
Publicado: (2020)

Alternative polyadenylation associated with prognosis and therapy in colorectal cancer
por: Zhang, Yi, et al.
Publicado: (2022)

The Role of Alternative Polyadenylation in the Regulation of Subcellular RNA Localization
por: Arora, Ankita, et al.
Publicado: (2022)

Alternative polyadenylation: methods, mechanism, function, and role in cancer
por: Zhang, Yi, et al.
Publicado: (2021)

Alternative polyadenylation of mRNA and its role in cancer
por: Yuan, Fuwen, et al.
Publicado: (2019)

Alternative polyadenylation is a determinant of oncogenic Ras function
por: Subramanian, Aishwarya, et al.
Publicado: (2021)

Diverse cell-specific patterns of alternative polyadenylation in Drosophila
por: Lee, Seungjae, et al.
Publicado: (2022)

RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery
por: Chatrikhi, Rakesh, et al.
Publicado: (2019)

Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma
por: Chen, Shi-lu, et al.
Publicado: (2021)

Profiling of alternative polyadenylation sites in luminal B breast cancer using the SAPAS method
por: WANG, XINMEI, et al.
Publicado: (2015)

Genetic and genomic stability across lymphoblastoid cell line expansions
por: Scheinfeldt, Laura B., et al.
Publicado: (2018)

Coordination of Alternative Splicing and Alternative Polyadenylation revealed by Targeted Long-Read Sequencing
por: Zhang, Zhiping, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q7mrl9nfe0v6ij6cnmc0a3v867