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Global Metabolic Profiling of Infection by an Oncogenic Virus: KSHV Induces and Requires Lipogenesis for Survival of Latent Infection

Like cancer cells, virally infected cells have dramatically altered metabolic requirements. We analyzed global metabolic changes induced by latent infection with an oncogenic virus, Kaposi's Sarcoma-associated herpesvirus (KSHV). KSHV is the etiologic agent of Kaposi's Sarcoma (KS), the mo...

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Detalles Bibliográficos
Autores principales: Delgado, Tracie, Sanchez, Erica L., Camarda, Roman, Lagunoff, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420960/
https://www.ncbi.nlm.nih.gov/pubmed/22916018
http://dx.doi.org/10.1371/journal.ppat.1002866