Convergent Evolution of Argonaute-2 Slicer Antagonism in Two Distinct Insect RNA Viruses

RNA interference (RNAi) is a major antiviral pathway that shapes evolution of RNA viruses. We show here that Nora virus, a natural Drosophila pathogen, is both a target and suppressor of RNAi. We detected viral small RNAs with a signature of Dicer-2 dependent small interfering RNAs in Nora virus inf...

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Detalles Bibliográficos
Autores principales: van Mierlo, Joël T., Bronkhorst, Alfred W., Overheul, Gijs J., Sadanandan, Sajna A., Ekström, Jens-Ola, Heestermans, Marco, Hultmark, Dan, Antoniewski, Christophe, van Rij, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420963/
https://www.ncbi.nlm.nih.gov/pubmed/22916019
http://dx.doi.org/10.1371/journal.ppat.1002872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420963/
https://www.ncbi.nlm.nih.gov/pubmed/22916019
http://dx.doi.org/10.1371/journal.ppat.1002872

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