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Convergent Evolution of Argonaute-2 Slicer Antagonism in Two Distinct Insect RNA Viruses
RNA interference (RNAi) is a major antiviral pathway that shapes evolution of RNA viruses. We show here that Nora virus, a natural Drosophila pathogen, is both a target and suppressor of RNAi. We detected viral small RNAs with a signature of Dicer-2 dependent small interfering RNAs in Nora virus inf...
Autores principales: | van Mierlo, Joël T., Bronkhorst, Alfred W., Overheul, Gijs J., Sadanandan, Sajna A., Ekström, Jens-Ola, Heestermans, Marco, Hultmark, Dan, Antoniewski, Christophe, van Rij, Ronald P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420963/ https://www.ncbi.nlm.nih.gov/pubmed/22916019 http://dx.doi.org/10.1371/journal.ppat.1002872 |
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