17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells

Hsp90 chaperone has been identified as an attractive pharmacological target to combat cancer. However, some metastatic tumors either fail to respond to Hsp90 inhibition or show recovery necessitating irreversible therapeutic strategies. In response to this enforced senescence has been proposed as an...

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Detalles Bibliográficos
Autores principales: Sarangi, Upasana, Paithankar, Khande Rao, Kumar, Jonnala Ujwal, Subramaniam, Vaidyanathan, Sreedhar, Amere Subbarao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422084/
https://www.ncbi.nlm.nih.gov/pubmed/22915839
http://dx.doi.org/10.4137/DTI.S9943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422084/
https://www.ncbi.nlm.nih.gov/pubmed/22915839
http://dx.doi.org/10.4137/DTI.S9943

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