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Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation
BACKGROUND: Decorin is a multifunctional molecule of the extracellular matrix and impedes different kinds of tumor cell growth, but the role and molecular mechanism by which decorin inhibits HepG2 cells is not fully understood. Our objective was to construct recombinant human decorin (pcDNA3.1-DCN)...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422087/ https://www.ncbi.nlm.nih.gov/pubmed/22927763 http://dx.doi.org/10.2147/OTT.S32918 |