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Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation

BACKGROUND: Decorin is a multifunctional molecule of the extracellular matrix and impedes different kinds of tumor cell growth, but the role and molecular mechanism by which decorin inhibits HepG2 cells is not fully understood. Our objective was to construct recombinant human decorin (pcDNA3.1-DCN)...

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Detalles Bibliográficos
Autores principales: Zhang, Yucheng, Wang, Yali, Du, Zhenwu, Wang, Qian, Wu, Mei, Wang, Xiaofeng, Wang, Lingling, Cao, Linlin, Hamid, Abdu Selim, Zhang, Guizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422087/
https://www.ncbi.nlm.nih.gov/pubmed/22927763
http://dx.doi.org/10.2147/OTT.S32918