Cargando…

Recombinant human decorin suppresses liver HepG2 carcinoma cells by p21 upregulation

BACKGROUND: Decorin is a multifunctional molecule of the extracellular matrix and impedes different kinds of tumor cell growth, but the role and molecular mechanism by which decorin inhibits HepG2 cells is not fully understood. Our objective was to construct recombinant human decorin (pcDNA3.1-DCN)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yucheng, Wang, Yali, Du, Zhenwu, Wang, Qian, Wu, Mei, Wang, Xiaofeng, Wang, Lingling, Cao, Linlin, Hamid, Abdu Selim, Zhang, Guizhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422087/ https://www.ncbi.nlm.nih.gov/pubmed/22927763 http://dx.doi.org/10.2147/OTT.S32918

Ejemplares similares

Acrylamide induces HepG2 cell proliferation through upregulation of miR-21 expression
por: Xu, Yuyu, et al.
Publicado: (2019)

Bombyxin II Regulates Glucose Absorption and Glycogen Synthesis through the PI3K Signaling Pathway in HepG2 Cells
por: Yang, Hongliang, et al.
Publicado: (2021)

Decorin inhibits proliferation and metastasis in human bladder cancer cells by upregulating P21
por: Chen, Hongjie, et al.
Publicado: (2022)

Detection of micrometastases in lung cancer with magnetic nanoparticles and quantum dots
por: Wang, Yali, et al.
Publicado: (2012)

MicroRNA-21 regulates the expression of BTG2 in HepG2 liver cancer cells
por: MAO, BIJING, et al.
Publicado: (2015)

GPR21 Inhibition Increases Glucose-Uptake in HepG2 Cells
por: Kinsella, Gemma K., et al.
Publicado: (2021)

Selectivity of biopolymer membranes using HepG2 cells
por: Lü, Dongyuan, et al.
Publicado: (2015)

Anti-tumor effect of volatile oil from Houttuynia cordata Thunb. on HepG2 cells and HepG2 tumor-bearing mice
por: Yang, Linsong, et al.
Publicado: (2019)

Metabolic Disorder of Extracellular Matrix Mediated by Decorin Upregulation Is Associated With Brain Arteriovenous Malformation Diffuseness
por: Li, Maogui, et al.
Publicado: (2020)

Riboflavin deficiency induces a significant change in proteomic profiles in HepG2 cells
por: Xin, Zhonghao, et al.
Publicado: (2017)

Knockdown of nucleophosmin induces S-phase arrest in HepG2 cells
por: Wang, Qing-Qing, et al.
Publicado: (2011)

Chrysophanol localizes in mitochondria to promote cell death through upregulation of mitochondrial cyclophilin D in HepG2 cells
por: Xie, Yu, et al.
Publicado: (2021)

The Antiapoptosis Effect of Glycyrrhizate on HepG2 Cells Induced by Hydrogen Peroxide
por: Su, Miao, et al.
Publicado: (2016)

Differential Inhibite Effect of Xanthohumol on HepG2 Cells and Primary Hepatocytes
por: Zhang, Xiuli, et al.
Publicado: (2022)

PDCD2 sensitizes HepG2 cells to sorafenib by suppressing epithelial-mesenchymal transition
por: Liu, Hongyu, et al.
Publicado: (2019)

Effects of knockout of lincRNA-p21 on the proliferation, migration and invasion ability of HepG2 liver cancer cells
por: Wang, Tongshan, et al.
Publicado: (2019)

Preparation of honokiol nanoparticles by liquid antisolvent precipitation technique, characterization, pharmacokinetics, and evaluation of inhibitory effect on HepG2 cells
por: Wu, Weiwei, et al.
Publicado: (2018)

Selenocystine against methyl mercury cytotoxicity in HepG2 cells
por: Wang, Han, et al.
Publicado: (2017)

Zebularine upregulates expression of CYP genes through inhibition of DNMT1 and PKR in HepG2 cells
por: Nakamura, Kazuaki, et al.
Publicado: (2017)

Allicin and Capsaicin Ameliorated Hypercholesterolemia by Upregulating LDLR and Downregulating PCSK9 Expression in HepG2 Cells
por: Nawaka, Nantiya, et al.
Publicado: (2022)

Embelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway
por: TAGHIYEV, ASAF, et al.
Publicado: (2012)

Cholesterol-lowing effect of taurine in HepG2 cell
por: Guo, Junxia, et al.
Publicado: (2017)

TLR3 Activation of Hepatic Stellate Cell Line Suppresses HBV Replication in HepG2 Cells
por: Zhang, Biao, et al.
Publicado: (2018)

Inhibitory effect of lingonberry extract on HepG2 cell proliferation, apoptosis, migration, and invasion
por: Zhu, Liangyu, et al.
Publicado: (2022)

Diosmetin induces apoptosis by upregulating p53 via the TGF-β signal pathway in HepG2 hepatoma cells
por: LIU, BIN, et al.
Publicado: (2016)

Effect of FABP5 gene silencing on the proliferation, apoptosis and invasion of human gastric SGC-7901 cancer cells
por: Zhao, Guanjie, et al.
Publicado: (2017)

TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK–STAT signaling pathway
por: Zhu, X, et al.
Publicado: (2016)

A proteomic analysis of mushroom polysaccharide-treated HepG2 cells
por: Chai, Yangyang, et al.
Publicado: (2016)

Artificial cells eavesdropping on HepG2 cells
por: Westensee, Isabella Nymann, et al.
Publicado: (2023)

An ‘activatable’ aptamer-based fluorescence probe for the detection of HepG2 cells
por: Lai, Zongqiang, et al.
Publicado: (2017)

Downregulation of HBx Restrains Proliferation, Migration, and Invasion of HepG2 Cells
por: Huang, Chaoqun, et al.
Publicado: (2021)

Selection of Suitable Reference Genes for qPCR Gene Expression Analysis of HepG2 and L02 in Four Different Liver Cell Injured Models
por: Chen, Jiyu, et al.
Publicado: (2020)

PD173074 blocks G1/S transition via CUL3-mediated ubiquitin protease in HepG2 and Hep3B cells
por: Qiao, Chuchu, et al.
Publicado: (2020)

Rosemary Extracts Upregulate Nrf2, Sestrin2, and MRP2 Protein Level in Human Hepatoma HepG2 Cells
por: Tong, Xiao-pei, et al.
Publicado: (2017)

Anticancer Effects of Bufalin on Human Hepatocellular Carcinoma HepG2 Cells: Roles of Apoptosis and Autophagy
por: Miao, Qing, et al.
Publicado: (2013)

Veratramine suppresses human HepG2 liver cancer cell growth in vitro and in vivo by inducing autophagic cell death
por: Yin, Linlin, et al.
Publicado: (2020)

The Mechanism by Which Amentoflavone Improves Insulin Resistance in HepG2 Cells
por: Zheng, Xiaoke, et al.
Publicado: (2016)

Inhibitory Effect of Gardenoside on Free Fatty Acid-Induced Steatosis in HepG2 Hepatocytes
por: Liang, Huiqing, et al.
Publicado: (2015)

Preparation of β-CD-Ellagic Acid Microspheres and Their Effects on HepG2 Cell Proliferation
por: Wang, Hongkai, et al.
Publicado: (2017)

DNMT1/PKR double knockdowned HepG2 (HepG2-DP) cells have high hepatic function and differentiation ability
por: Tanaka-yachi, Rieko, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hthmnbpcvphr8v8fn95hto9one