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Incorporation of a selective sigma-2 receptor ligand enhances uptake of liposomes by multiple cancer cells
BACKGROUND: The sigma-2 receptor is an attractive target for tumor imaging and targeted therapy because it is overexpressed in multiple types of solid tumors, including prostate cancer, breast cancer, and lung cancer. SV119 is a synthetic small molecule that binds to sigma-2 receptors with high affi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422102/ https://www.ncbi.nlm.nih.gov/pubmed/22927761 http://dx.doi.org/10.2147/IJN.S31981 |