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Incorporation of a selective sigma-2 receptor ligand enhances uptake of liposomes by multiple cancer cells

BACKGROUND: The sigma-2 receptor is an attractive target for tumor imaging and targeted therapy because it is overexpressed in multiple types of solid tumors, including prostate cancer, breast cancer, and lung cancer. SV119 is a synthetic small molecule that binds to sigma-2 receptors with high affi...

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Detalles Bibliográficos
Autores principales: Zhang, Yifei, Huang, Yixian, Zhang, Peng, Gao, Xiang, Gibbs, Robert B, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422102/
https://www.ncbi.nlm.nih.gov/pubmed/22927761
http://dx.doi.org/10.2147/IJN.S31981