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HLA-A*0206 with TLR3 Polymorphisms Exerts More than Additive Effects in Stevens-Johnson Syndrome with Severe Ocular Surface Complications

BACKGROUND: Stevens-Johnson syndrome (SJS) is an acute inflammatory vesiculobullous reaction of the skin and mucosa, often including the ocular surface, and toxic epidermal necrolysis (TEN) occurs with its progression. Although SJS/TEN is thought to be initiated by certain types of medication couple...

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Detalles Bibliográficos
Autores principales: Ueta, Mayumi, Tokunaga, Katsushi, Sotozono, Chie, Sawai, Hiromi, Tamiya, Gen, Inatomi, Tsutomu, Kinoshita, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422242/
https://www.ncbi.nlm.nih.gov/pubmed/22912896
http://dx.doi.org/10.1371/journal.pone.0043650